TPC26 agenda is currently being compiled — sign up for an announcement once it is ready.
Confirmed keynotes and invited talks include:

Under Secretary for Science, Department of Energy
(Conference Keynote)

Director, Office of Advanced Cyberinfrastructure, US National Science Foundation

Associate Laboratory Director, Professor of Computer Science, Argonne National Laboratory

Director, RIKEN Center for Computational Science

Global Head of Core and Advanced Computing, Amazon Web Services

Vice Provost for AI, Charles and Lisa Simonyi Endowed Chair for Artificial Intelligence and Emerging Technologies, University of Washington

Director, Mathematics and Computer Science Division, Argonne National Laboratory

Professor, Institute of Science Tokyo

Data Science and Learning Division Director, Argonne National Laboratory

Executive Director, Texas Advanced Computing Center (TACC) and Associate Vice President for Research, UT-Austin

R&D Lead, Senior Computer Scientist, Argonne National Laboratory

Samir and Puja Kaul Director of the Michigan Institute for Computational Discovery and Engineering and Professor, University of Michigan Aerospace Department
This year, TPC26 will feature forty 90-minute breakout sessions on June 2 and 3, organized into eight parallel tracks around these topics:
Breakout slots will accommodate existing TPC working groups and Birds-of-a-Feather (BOF) sessions. The latter may be initiatives or multi-institutional projects seeking collaborators, prospective new TPC working groups, or other topics of general interest to the TPC community.
Please use these forms to propose BOF sessions and lightning talks:
For reference as to what the full TPC26 agenda will look like, please see the TPC25 agenda here and the TPC25 session descriptions here.